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The Nutty Professor Eddie Murphy 1996

Weird Science

10 Weird Movie Substances That Had Hilarious Consequences

Catch The Nutty Professor this month on IFC.

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Photo Credit: Universal Pictures/Everett Collection

If you’ve ever opened your refrigerator to find some seriously gnarly days-old potato salad, then you know that sometimes the most harmless-seeming things can turn freaky. Movies have conjured up some truly bizarre stuff, often the work of crazed scientists. Before you catch The Nutty Professor on IFC, check out some of the icky-est, gooey-ist and just plain weird substances on the big screen.

10. Flubber

Walt Disney Studios

Professor Brainard’s “flying rubber” increases its speed every time it bounces, and increases the chaos, destruction and unlikely basketball-dunkage of anyone who uses it. Thankfully the movie ends before its thermodynamic impossibility cause the incineration of the entire universe.

9. Quantonium, Monsters Vs. Aliens

Monsters Vs Aliens

In Monsters vs. Aliens, both action-packed parties are battling over Quantonium, an exotic material which massively empowers anyone who holds it. Literally in the case of Susan Murphy, whose exposure turns her into Ginormica and enables her to fight against Gallaxhar’s invasion force.

8. Sustengo, Little Fockers

Universal Pictures

After finally finding favor with his hard-bitten father-in-law, Greg Focker (Ben Stiller) finds himself strapped for cash and starts promoting Sustengo, an erectile dysfunction drug. Which means leaving boxes of ED drugs lying around a family who can’t even use a toilet without triggering a series of hilarious misunderstandings.

7. Iocane, Princess Bride

20th Century Fox

Iocane is a deadly poison with no odor or taste that dissolves instantly in any liquid. The perfect tool for murder isn’t usually hilarious, but The Princess Bride makes everything funny. Hero Westley (Cary Elwes) tricks cunning Vizzini (Wallace Shawn) into drinking the poison in a game of wits. Vizzini lost, not knowing that the answer is “Don’t drink anything offered by someone who just talked about how awesome their poison is.”

6. PX-41, Despicable Me 2

Universal Pictures

The mutation compound engineered by PX-Labs turns anything into a purple, fluffy, indestructible killing machine. And when Despicable Me‘s famous Minions are dosed with it, look out. Dr. Nefario (Russell Brand) crafts an antidote, PX-41 Antidote, proving he’s much better with chemicals than he is with names.

5. Mood Slime, Ghostbusters II

Mood Slime
Columbia Pictures

When the Ghostbusters came back for their 1989 sequel, the slime they encountered was sillier and scarier. The “Mood Slime” was a special form of ectoplasm utterly saturated in the emotions of everyone and everything around it. And while our heroes energize some positive vibes with Aretha Franklin tunes, the entire city of New York’s psychic outpourings are filling the sewers with something distinctly less positive.

4. The Stuff

The Stuff
New World Pictures

A science fiction soft-serve satire, The Stuff is about an oddly organic treat which is utterly delicious and zero calories. In fact it’s negative calories, because if you eat enough it’ll take over your brain and hollow you out from the inside.

3. Miracle Weight Loss Serum, The Nutty Professor

Buddy Love
Universal Pictures

The core component of The Nutty Professor‘s plot is a miraculous weight loss serum, a simple fluid which re-engineers human DNA all by itself. This allows sweet but sizable Sherman Klump (Eddie Murphy) to transform into the tight, toned and turbocharged Buddy Love (Murphy again). The serum is revealed to be fatally dangerous, but anything which allows Eddie Murphy to play himself cranked up to the max is pure comedy gold.

2. Cobalt Thorium G, Dr. Strangelove

Dr Strangelove
Columbia Pictures

Dr Strangelove or: How I Learned To Stop Worrying and Love The Bomb is about a bomb built with Cobalt Thorium G. It’s a doomsday device designed to annihilate all human civilization and is, slightly worryingly, based on the least fictional materials on this list. Cobalt and thorium both have applications in nuclear weapon design. Luckily we haven’t got them up to G yet.

1. Ectoplasm, Ghostbusters

Columbia Pictures

The Ghostbusters live in a world where ghosts are real but physics is still in charge. So while the ghouls are flung around with proton packs, they get the boys in grey back with their appalling ectoplasm, or slime, trail. As Venkman says, getting covered in the stuff will make you feel all funky.


Rev Up

Your Portlandia Personality Test

The New Portlandia Webseries Is Going Your Way

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Carrie and Fred understand that although we have so much in common, we’re each so beautifully unique and different. To help us navigate those differences, Portlandia has found an easy and honest way to embrace our special selves in the form of a progressive new traffic system: a specific lane for every kind of driver. It’s all in honor of the show’s 8th and final season, and it’s all presented by Subaru.

Ready to find out who you really are? Match your personality to a lane and hop on the expressway to self-understanding.

Lane 10: Trucks Piled With Junk

Your junk is falling out of your trunk. Shake a tail light, people — this lane is for you.

Lane 33: Twins

You’re like a Gemini, but waaaay more pedestrian. Maybe you and a friend just wear the same outfits a lot. Who cares, it’s just twinning enough to make you feel special.

Lane 27: Broken Windows

Bad luck follows you around and everyone knows it. Your proverbial seat is always damp from proverbial rain. Is this the universe telling you to swallow your pride? Yes.

Lane 69: Filthy Cars

You’re all about convenience. Getting your car washed while you drive is a no-brainer.

Lane 43: Newly Divorced Singles

It’s been a while since you’ve driven alone, and you don’t know the rules of the road anymore. What’s too fast? What’s too slow? Are you sending the right signals? Don’t worry, the breakdown lane is nearby if you need it.

Still can’t find a lane to match your personality? Check out all the videos here. And see the final season of Portlandia this spring on IFC.


Give Back

Last-Minute Holiday Gift Guide

Hits from the '80s are on repeat all Christmas Eve and Day on IFC.

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GIFs via Giphy, Photos via The Everett Collection

It’s the final countdown to Christmas and thanks to IFC’s movie marathon all Christmas Eve and Christmas Day, you can revel in classic ’80s films AND find inspiration for your last-minute gifts. Here are our recommendations, if you need a head start:

Musical Instrument

Great analog entertainment substitute when you refuse to give your kid the Nintendo Switch they’ve been drooling over.

Breakfast In Bed

Any significant other or child would appreciate these Uncle Buck-approved flapjacks. Just make sure you’re not stuck on clean up duty.

Cocktail Supplies

You’ll need them to get through the holidays.

Dance Lessons

So you can learn to shake-shake-shake (unless you know ghosts willing to lend a hand).

Comfy Clothes

With all the holiday meals, there may be some…embigenning.

Get even more great inspiration all Christmas Eve and Day on IFC, and remember…


A-O Rewind

Celebrating Portlandia One Sketch at a Time

The final season of Portlandia approaches.

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GIFs via Giphy

Most people measure time in minutes, hours, days, years…At IFC, we measure it in sketches. And nothing takes us way (waaaaaay) back like Portlandia sketches. Yes, there’s a Portlandia milepost from every season that changed the way we think, behave, and pickle things. In honor of Portlandia’s 8th and final season, Subaru presents a few of our favorites.


Put A Bird On It

Portlandia enters the pop-culture lexicon and inspires us to put birds on literally everything.

Colin the Chicken

Who’s your chicken, really? Behold the emerging locavore trend captured perfectly to the nth degree.

Dream Of The ’90s

This treatise on Portland made it clear that “the dream” was alive and well.

No You Go

We Americans spend most of our lives in cars. Fortunately, there’s a Portlandia sketch for every automotive situation.

A-O River!

We learned all our outdoor survival skills from Kath and Dave.

One More Episode

The true birth of binge watching, pre-Netflix. And what you’ll do once Season 8 premieres.

Catch up on Portlandia’s best moments before the 8th season premieres January 18th on IFC.